Concepedia

High-content Screening

High-Content Screening is a multiparametric imaging-based analysis method that enables the simultaneous quantification of cellular phenotypes across diverse biological targets and functional pathways within intact cells, distinguished by its integration of automated microscopy, fluorescent labeling, and advanced image analysis algorithms to extract spatial, temporal, and intensity data at single-cell resolution.

708

Publications

33.8K

Citations

4.3K

Authors

1.1K

Institutions

Publications per year

2017–2026

269

Variants

Hcs

Parents

Publications

708

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Christian Hansen, Élodie Angot, Ann‐Louise Bergström et al. · Journal of Clinical Investigation · 2011 · 837 citations · Full text

, , +17

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

Peter J. O’Brien, William Irwin, Dolores Diaz et al. · Archives of Toxicology · 2006 · 609 citations

, , +16

Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

Chao Wang, Michael E. Ward, Robert Y. Chen et al. · Stem Cell Reports · 2017 · 465 citations · Full text

, , +17

Classifying and segmenting microscopy images with deep multiple instance learning

Oren Kraus, Jimmy Ba, Brendan J. Frey · Bioinformatics · 2016 · 449 citations · Full text

, , +17

A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods

Justin C. Yarrow, Zachary E. Perlman, Nicholas J. Westwood et al. · BMC Biotechnology · 2004 · 368 citations · Full text

, , +14

1–5 of 708

Authors

4.3K

  1. DL
    D. Lansing Taylor

    Carnegie Mellon University, United States

    11 publications · 793 citations

    12

    h-index

  2. LT
    Laia Tolosa

    Instituto de Investigación Sanitaria La Fe, Spain

    8 publications · 442 citations

    8

    h-index

  3. ST
    Stephen T.C. Wong

    Methodist Hospital, United States

    8 publications · 376 citations

    8

    h-index

  4. KA
    Kenneth A. Giuliano

    University of Pittsburgh, United States

    6 publications · 582 citations

    7

    h-index

  5. JS
    John S. Lazo

    University of Pittsburgh, United States

    7 publications · 337 citations

    7

    h-index

1–5 of 4.3K

Institutions

1.1K

  1. Harvard University

    Cambridge, United States

    19 h-index

    73 publications

    5.2K citations

  2. University of Pittsburgh

    Pittsburgh, United States

    17 h-index

    120 publications

    6.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    68 publications

    4.2K citations

  4. Inserm

    Paris, France

    14 h-index

    67 publications

    3.3K citations

  5. Heidelberg University

    Heidelberg, Germany

    13 h-index

    58 publications

    1.8K citations

  6. University of Toronto

    Toronto, Canada

    12 h-index

    73 publications

    6.6K citations

  7. Trinity College Dublin

    Dublin, Ireland

    11 h-index

    77 publications

    3.7K citations

  8. University of British Columbia

    Vancouver, Canada

    11 h-index

    76 publications

    2.2K citations

1–8 of 1.1K

Venues

  1. SLAS DISCOVERY

    81 publications · 3K citations

    31

    h-index

  2. PLoS ONE

    35 publications · 1.8K citations

    24

    h-index

  3. Assay and Drug Development Technologies

    25 publications · 1.1K citations

    20

    h-index

  4. Scientific Reports

    20 publications · 1.1K citations

    17

    h-index

  5. Nature Communications

    9 publications · 578 citations

    11

    h-index

1–5