Concepedia

Identifying off-target effects and hidden phenotypes of drugs in human cells

Marnie L. MacDonald, Jane E. Lamerdin, Stephen Owens, Brigitte H. Keon, Graham K. Bilter, Zhidi Shang, Zhengping Huang, Helen Yu, Jennifer Dias, Tomoe Minami,

Nature Chemical Biology · 2006 · 297 citations · 38 references

DOI

Concepts

References

38

Hierarchical Grouping to Optimize an Objective Function

Joe H. Ward · Journal of the American Statistical Association · 1963 · 19.2K citations

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

Takeharu Nagai, Keiji Ibata, Eun Sun Park et al. · Nature Biotechnology · 2002 · 2.8K citations

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

Robert T. Nolte, G. Bruce Wisely, Stefan Westin et al. · Nature · 1998 · 1.9K citations

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Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation

Chang-Deng Hu, Yurii Chinenov, Tom K. Kerppola · Molecular Cell · 2002 · 1.6K citations · Full text

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The specificities of protein kinase inhibitors: an update

Jenny Bain, Hilary McLauchlan, Matthew Elliott et al. · Biochemical Journal · 2003 · 1.4K citations · Full text

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