Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

Robert T. Nolte, G. Bruce Wisely, Stefan Westin, +7

Nature

Signal TransductionBiochemistryMedicineMechanism Of ActionReceptor (Biochemistry) +3

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

Joseph Torchia, David W. Rose, Juan Inostroza, +4

Nature

Transcriptional RegulationSignal TransductionSignaling PathwayNatural SciencesTranscriptional Co-activator P/cip +7

Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors

Sumito Ogawa, Jean Lozach, Christopher Benner, +8

Cell

Toll-like ReceptorsSignal TransductionImmunologyMolecular DeterminantsReceptor (Biochemistry) +4

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

Eileen M. McInerney, David W. Rose, Sarah E. Flynn, +10

Genes & Development

Transcriptional Activation by NF-κB Requires Multiple Coactivators

Kelly-Ann Sheppard, David W. Rose, Zaffar Haque, +7

Molecular and Cellular Biology

InflammationTranscriptional ActivationTranscriptional RegulationSignal TransductionSignaling Pathway +13

Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators

Stefan Westin, Riki Kurokawa, Robert T. Nolte, +6

Nature

Signal TransductionG Protein-coupled ReceptorReceptor (Biochemistry)Molecular BiologyNuclear Organization +2

Farnesoid X Receptor Regulates Bile Acid-Amino Acid Conjugation

P Pircher, Jennifer L. Kitto, Mary Petrowski, +4

Journal of Biological Chemistry

Discovery of XL335 (WAY-362450), a Highly Potent, Selective, and Orally Active Agonist of the Farnesoid X Receptor (FXR)

Brenton Flatt, Richard Martin, Tielin Wang, +14

Journal of Medicinal Chemistry

Chronic AdministrationMolecular BiologyFarnesoid X ReceptorPharmacotherapyVivo Optimization +17

Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription

Juan Llopis, Stefan Westin, Mercedes Ricote, +8

Proceedings of the National Academy of Sciences

Retinoic Acid ReceptorEstrogen ReceptorMolecular BiologyNuclear Hormone ReceptorsPeroxisome Proliferator-activated Receptor +17

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion.

Catherine Legraverend, Agneta Mode, Stefan Westin, +4

Molecular Endocrinology

GeneticsSequence InformationReproductive BiologyEpigeneticsGene Subfamily Members +17