Concepedia

Carnosic acid ameliorated Aβ-mediated (amyloid-β peptide) toxicity, cholinergic dysfunction and mitochondrial defect in <i>Caenorhabditis elegans</i> of Alzheimer's Model

Yun Chen, Yun Chen, Yarong Wang, Qiao Qin, Yali Zhang, Lingling Xie, Jie Xiao, Yong Cao, Zuanxian Su, Yunjiao Chen,

Food & Function · 2022 · 25 citations · 49 references

DOI

Concepts

Abstract

Carnosic acid reduced Aβ deposition and Aβ-mediated neurotoxicity, and ameliorated cholinergic dysfunction and mitochondrial disorders in the C. elegans model of Alzheimer's disease.

References

49

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

P. Hemachandra Reddy, M. Flint Beal · Trends in Molecular Medicine · 2008 · 970 citations · Full text

, , +17

The cost of Alzheimer's disease in China and re‐estimation of costs worldwide

Jianping Jia, Cuibai Wei, Shuoqi Chen et al. · Alzheimer s & Dementia · 2018 · 754 citations

, , +17

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

Vincenzo Sorrentino, Mario Romani, Laurent Mouchiroud et al. · Nature · 2017 · 639 citations · Full text

, , +12

Alzheimer's disease

Lennart Mucke · Nature · 2009 · 459 citations

, , +17

Amyloid-β-Induced Pathological Behaviors Are Suppressed by<i>Ginkgo biloba</i>Extract EGb 761 and Ginkgolides in Transgenic<i>Caenorhabditis elegans</i>

Yanjue Wu, Zhixin Wu, Peter Butko et al. · Journal of Neuroscience · 2006 · 411 citations · Full text

, , +17