P. Hemachandra Reddy

Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

Maria Mańczak, Thimmappa S. Anekonda, Edward Henson et al. · Human Molecular Genetics · 2006 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

P. Hemachandra Reddy, M. Flint Beal · Trends in Molecular Medicine · 2008 · 970 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

Maria Mańczak, Marcus J. Calkins, P. Hemachandra Reddy · Human Molecular Genetics · 2011 · 813 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

Marcus J. Calkins, Maria Mańczak, Peizhong Mao et al. · Human Molecular Genetics · 2011 · 646 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons

Maria Mańczak, Peizhong Mao, Markus J. Calkins et al. · Journal of Alzheimer s Disease · 2010 · 467 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17