Hemin enhances radiosensitivity of lung cancer cells through ferroptosis

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.5K citations · Full text

Life Sciences, Molecular Biology, Oncology +12

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth et al. · Nature Cell Biology · 2014 · 3.6K citations

Medicine, Nephrology, Pathobiology +10

Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Xiaofang Sun, Zhanhui Ou, Ruochan Chen et al. · Hepatology · 2015 · 2K citations · Full text

Life Sciences, Cell Biology, Oncology +17

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

Irina Ingold, Carsten Berndt, Sabine Schmitt et al. · Cell · 2017 · 1.6K citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +13