Concepedia

Naringenin prolongs lifespan and delays aging mediated by IIS and MAPK in <i>Caenorhabditis elegans</i>

Yue Ge, Huibin Chen, Jilite Wang, Guishan Liu, Steve W. Cui, Ji Kang, Yumei Jiang, Hao Wang

Food & Function · 2021 · 54 citations · 46 references

DOI

Concepts

Abstract

. Moreover, the selected mutant strains were used and molecular docking was conducted to further suggest that IIS and MAPK pathways could be involved in the NN-mediated longevity-promoting effect.

References

46

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

Laura A. Herndon, Peter J. Schmeissner, Justyna M. Dudaronek et al. · Nature · 2002 · 1.2K citations

, , +16

Traditional Chinese medicine network pharmacology: theory, methodology and application

Shao Li, Bo Zhang · Chinese Journal of Natural Medicines · 2014 · 956 citations

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Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

Jennifer M. A. Tullet, Maren Hertweck, Jae Hyung An et al. · Cell · 2008 · 931 citations · Full text

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Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs

Marianna Zolotovskaia, Maxim Sorokin, Anna A. Emelianova et al. · Frontiers in Pharmacology · 2019 · 535 citations · Full text

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Subacute Combined Degeneration, Pernicious Anemia and Gastric Neuroendocrine Tumor Occured Simultaneously Caused by Autoimmune Gastritis

Nan Zhang, Ruihua Li, Lin Ma et al. · Frontiers in Neuroscience · 2019 · 493 citations · Full text

, , +14