Divergent functions of IL-17-family cytokines in DSS colitis: Insights from a naturally-occurring human mutation in IL-17F

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

Wolfgang Hueber, Bruce E. Sands, Steve Lewitzky et al. · Gut · 2012 · 1.5K citations · Full text

Life Sciences, Immunology, Pharmacotherapy +15

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

Anne Puel, Sophie Cypowyj, Jacinta Bustamante et al. · Science · 2011 · 1K citations

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Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

Harumichi Ishigame, Shigeru Kakuta, Takeshi Nagai et al. · Immunity · 2009 · 1K citations · Full text

Life Sciences, Immunology, Microbiology +17

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

William O’Connor, Masahito Kamanaka, Carmen J. Booth et al. · Nature Immunology · 2009 · 753 citations · Full text

Life Sciences, Immunology, Pathology +17

Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

Jacob S. Lee, Cristina M. Tato, Barbara Joyce-Shaikh et al. · Immunity · 2015 · 738 citations · Full text

Life Sciences, Immunology, Pathology +10