IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis

Yutaka Komiyama, Susumu Nakae, Taizo Matsuki, +5

The Journal of Immunology

Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

Harumichi Ishigame, Shigeru Kakuta, Takeshi Nagai, +11

Immunity

InflammationHost ResponseAllergyPathogenesisImmunology +8

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

Shinobu Saijo, Satoshi Ikeda, Keiko Yamabe, +18

Immunity

Antifungal AgentMicrobial PathogensFungal Cell BiologyTh17 Cell DifferentiationFungal Pathogen +13

KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

Dietmar Herndler‐Brandstetter, Harumichi Ishigame, Ryo Shinnakasu, +13

Immunity

Autoimmune DiseaseAdaptive Immune SystemImmunologyAutoimmunityT Cell Immunity +6

The liver–brain–gut neural arc maintains the Treg cell niche in the gut

Toshiaki Teratani, Yohei Mikami, Nobuhiro Nakamoto, +24

Nature

Treg Cell NicheDevelopmental BiologyBiliary TractLiver–brain–gut Neural ArcLiver Physiology +7

Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection

Paula Licona-Limón, Jorge Henao‐Mejia, Angela Temann, +6

Immunity

IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8+ T cells

Masaki Tajima, Daiko Wakita, Daisuke Noguchi, +7

The Journal of Experimental Medicine

Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota

Ce Tang, Shigeru Kakuta, Kenji Shimizu, +8

Nature Immunology

InflammationMucosal ImmunologyImmunologyAutoimmunityTreg Cells +4

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells

Aoi Akitsu, Harumichi Ishigame, Shigeru Kakuta, +10

Nature Communications

CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis

Masanori A. Murayama, Shigeru Kakuta, Asuka Inoue, +21

Nature Communications