Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

Anne Puel, Sophie Cypowyj, Jacinta Bustamante, +21

Science

ImmunodeficienciesImmunologyDermatologyImmunotherapyInflammation +15

Gain-of-function human <i>STAT1</i> mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

Luyan Liu, Satoshi Okada, Xiao‐Fei Kong, +58

The Journal of Experimental Medicine

Microbial PathogensImmunodeficienciesInnate Immune SystemImmunologyImmune Regulation +19

Deep Dermatophytosis and Inherited CARD9 Deficiency

Fanny Lanternier, Saad Pathan, Quentin B. Vincent, +29

New England Journal of Medicine

Distinct Innate Immune Responses to Infection and Wounding in the C. elegans Epidermis

Nathalie Pujol, Sophie Cypowyj, Katja Ziegler, +6

Current Biology

InflammationHost ResponsePathogenesisImmunologyInnate Immune System +8

An ACT1 Mutation Selectively Abolishes Interleukin-17 Responses in Humans with Chronic Mucocutaneous Candidiasis

Bertrand Boisson, Chenhui Wang, Vincent Pedergnana, +10

Immunity

InflammationAllergyPathogenesisImmunologyChronic Mucocutaneous Candidiasis +4

Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis

Yun Ling, Sophie Cypowyj, Caner Aytekin, +17

The Journal of Experimental Medicine

Antifungal Innate Immunity in C. elegans: PKCδ Links G Protein Signaling and a Conserved p38 MAPK Cascade

Katja Ziegler, C. Léopold Kurz, Sophie Cypowyj, +4

Cell Host & Microbe

Molecular ImmunologySignal TransductionAntifungal Innate ImmunitySignaling PathwayReceptor Tyrosine Kinase +8

New and recurrent gain-of-function <i>STAT1</i> mutations in patients with chronic mucocutaneous candidiasis from Eastern and Central Europe

Beáta Soltész, Beáta Tóth, Nadejda Shabashova, +15

Journal of Medical Genetics

Low Circulating Natural Killer Cell Counts are Associated With Severe Disease in Patients With Common Variable Immunodeficiency

Mikaël Ebbo, Laurence Gérard, Sabrina Carpentier, +9

EBioMedicine

Simple diagnosis of<i>STAT1</i>gain-of-function alleles in patients with chronic mucocutaneous candidiasis

Yoko Mizoguchi, Miyuki Tsumura, Satoshi Okada, +21

Journal of Leukocyte Biology

Diagnostic MycologyImmunodeficienciesImmunologyPathologyClinical Mycology +15