Bertrand Boisson

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard, Lindsey B. Rosen, Qian Zhang et al. · Science · 2020 · 2.8K citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu et al. · Science · 2020 · 2.4K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants

Aziz Belkadi, Alexandre Bolze, Yuval Itan et al. · Proceedings of the National Academy of Sciences · 2015 · 644 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Jérémie Rosain et al. · Science Immunology · 2021 · 631 citations · Full text

Life Sciences, Immunology, Infectious Diseases +11

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

Xianqin Zhang, Dusan Bogunovic, Béatrice Payelle‐Brogard et al. · Nature · 2014 · 566 citations · Full text

Life Sciences, Immunology, Molecular Genetics +10