Concepedia

Attenuation of Doxorubicin‐Induced Small Intestinal Mucositis by Pectins is Dependent on Pectin's Methyl‐Ester Number and Distribution

Martin Beukema, Éva Jermendi, Taco Koster, Kohji Kitaguchi, Bart J. de Haan, Marco Alexander van den Berg, Marijke M. Faas, Henk A. Schols, Paul de Vos

Molecular Nutrition & Food Research · 2021 · 34 citations · 23 references

DOIFull text

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Abstract

These pectin structures with stronger TLR2-inhibiting properties may prevent the development of doxorubicin-induced intestinal damage in patients undergoing chemotherapeutic treatment with doxorubicin.

References

23

Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

Mi Sun Jin, Sung Eun Kim, Jin Young Heo et al. · Cell · 2007 · 1.3K citations · Full text

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The burdens of cancer therapy

Linda S. Elting, Catherine D. Cooksley, Mark S. Chambers et al. · Cancer · 2003 · 610 citations · Full text

Management of oral and gastrointestinal mucositis: ESMO Clinical Practice Guidelines

Douglas E. Peterson, René‐Jean Bensadoun, Fausto Roila · Annals of Oncology · 2011 · 290 citations · Full text

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Dietary Fiber Pectin Directly Blocks Toll-Like Receptor 2–1 and Prevents Doxorubicin-Induced Ileitis

Neha M. Sahasrabudhe, Martin Beukema, Lingmin Tian et al. · Frontiers in Immunology · 2018 · 184 citations · Full text

Investigation of the non-esterified galacturonic acid distribution in pectin with endopolygalacturonase

Piet Daas, Karin Meyer-Hansen, Henk A. Schols et al. · Carbohydrate Research · 1999 · 177 citations

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