Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Axel T. Brünger, Paul D. Adams, G. Marius Clore et al. · Acta Crystallographica Section D Biological Crystallography · 1998 · 15.8K citations

Natural Sciences, Biophysics, Chemistry +17

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.7K citations

Life Sciences, Biochemistry, Biomolecular Modeling +16

Multiple sequence alignment with the Clustal series of programs

Nucleic Acids Research · 2003 · 4.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors

Adrian Ozinsky, David M. Underhill, Jason D. Fontenot et al. · Proceedings of the National Academy of Sciences · 2000 · 2.1K citations · Full text

Life Sciences, Immunology, Microbiology +17

Likelihood-enhanced fast translation functions

Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Laurent C. Storoni et al. · Acta Crystallographica Section D Biological Crystallography · 2005 · 1.6K citations · Full text

Life Sciences, Bioinformatics, Computational Chemistry +5