Concepedia

Saponins from Panax japonicus alleviate HFD-induced impaired behaviors through inhibiting NLRP3 inflammasome to upregulate AMPA receptors

Jinxin Wang, Dongfan Wang, Zhiyong Zhou, Xulan Zhang, Changcheng Zhang, Yumin He, Chaoqi Liu, Chengfu Yuan, Ding Yuan, Ting Wang

Neurochemistry International · 2021 · 21 citations · 35 references

DOI

Concepts

References

35

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature · 2012 · 2.9K citations · Full text

, , +14

NLRP3 inflammasome activation drives tau pathology

Christina Ising, Carmen Venegas, Shuangshuang Zhang et al. · Nature · 2019 · 1.5K citations · Full text

, , +12

Cognitive impairment following high fat diet consumption is associated with brain inflammation

Paul J. Pistell, Christopher D. Morrison, Sunita Gupta et al. · Journal of Neuroimmunology · 2009 · 590 citations

, , +15

Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke

David Y. Fann, Yun‐An Lim, Yi-Lin Cheng et al. · Molecular Neurobiology · 2017 · 320 citations

, , +12

NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation

Yuwen Zhang, Lei Liu, Y.-Z. Liu et al. · The International Journal of Neuropsychopharmacology · 2015 · 315 citations · Full text

, , +17