Concepedia

Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson’s disease model

Xiaofei Qiu, Qinghui Wang, Qinghui Wang, Liyan Hou, Cuili Zhang, Xiulan Zhao

Toxicology Letters · 2021 · 54 citations · 50 references

DOI

Concepts

References

50

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature · 2012 · 2.9K citations · Full text

, , +14

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

Gabriel T. Liberatore, Vernice Jackson‐Lewis, Slobodanka Vukosavić et al. · Nature Medicine · 1999 · 1K citations

, , +16

Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

Kazuhiro Imamura, Nozomi Hishikawa, Makoto Sawada et al. · Acta Neuropathologica · 2003 · 813 citations

, , +14

α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

Li Chen, Mel Β. Feany · Nature Neuroscience · 2005 · 614 citations

, , +17

Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies

Gaia Codolo, Nicoletta Plotegher, Tommaso Pozzobon et al. · PLoS ONE · 2013 · 575 citations · Full text

, , +17