Concepedia

Feeding induces cholesterol biosynthesis via the mTORC1–USP20–HMGCR axis

Xiao-Yi Lu, Xiongjie Shi, Ao Hu, Ju-Qiong Wang, Yi Ding, Wei Jiang, Ming Sun, Xiaolu Zhao, Jie Luo, Wei Qi,

Nature · 2020 · 277 citations · 22 references

DOI

Concepts

References

22

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

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AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

, , +15

Cholesterol Modification of Hedgehog Signaling Proteins in Animal Development

Jeffery A. Porter, Keith E. Young, Philip A. Beachy · Science · 1996 · 1.4K citations

, , +16

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

Peggy P. Hsu, Seong A. Kang, Jonathan Rameseder et al. · Science · 2011 · 1.1K citations · Full text

, , +15

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

Yonghao Yu, Sang-Oh Yoon, George Poulogiannis et al. · Science · 2011 · 875 citations

, , +17