Concepedia

Sirolimus for treatment of patients with inclusion body myositis: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2b trial

Olivier Benvéniste, Jean‐Yves Hogrel, Lisa Belin, M. Annoussamy, Damien Bachasson, Aude Rigolet, Pascal Laforêt, Gaëlle Dzangué-Tchoupou, Joe‐Elie Salem, Lee S. Nguyen,

The Lancet Rheumatology · 2020 · 73 citations · 25 references

DOI

Concepts

References

25

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Randy Strong, Z. Dave Sharp, James F. Nelson et al. · Nature · 2009 · 3.7K citations · Full text

, , +15

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

Greg M. Delgoffe, Kristen Pollizzi, Adam T. Waickman et al. · Nature Immunology · 2011 · 1.1K citations · Full text

, , +16

The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

Sokol Haxhinasto, Diane Mathis, Christophe Benoıst · The Journal of Experimental Medicine · 2008 · 719 citations · Full text

, , +17

MRI biomarker assessment of neuromuscular disease progression: a prospective observational cohort study

Jasper M. Morrow, Christopher D. J. Sinclair, Arne Fischmann et al. · The Lancet Neurology · 2015 · 341 citations · Full text

, , +15

Long-term observational study of sporadic inclusion body myositis

Olivier Benvéniste, Marguerite Guiguet, John Freebody et al. · Brain · 2011 · 312 citations · Full text

, , +15