Concepedia

Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway

Yijing Zhao, Lei Zhou, Hui Li, Tingge Sun, Wen Xue, Xueli Li, Ying Meng, Yán Li, Mengmeng Liu, Shanshan Liu,

Molecular Therapy — Nucleic Acids · 2020 · 127 citations · 37 references

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Abstract

functions as a critical epigenetic player in the regulation of mitochondrial metabolism of hepatoma cells, laying the foundation for further clarifying the roles of lncRNAs in tumor metabolic reprogramming.

References

37

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Michael Lazarou, Danielle A. Sliter, Lesley A. Kane et al. · Nature · 2015 · 2.7K citations

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BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

Kate McArthur, Lachlan Whitehead, John M. Heddleston et al. · Science · 2018 · 1K citations

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Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Christopher J L Murray, Katrina F Ortblad, Caterina Guinovart et al. · The Lancet · 2014 · 992 citations · Full text

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Mitochondrial transcription factor A regulates mtDNA copy number in mammals

Mats I. Ekstrand · Human Molecular Genetics · 2004 · 924 citations · Full text

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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

Jin‐Mi Heo, Alban Ordureau, João A. Paulo et al. · Molecular Cell · 2015 · 882 citations · Full text

, , +16