Concepedia

Lesley A. Kane

LA

Statistics

Publications

23

Citations

8.5K

H-Index

21

Active since

2006

Affiliations

Johns Hopkins University(Current)

Denali Therapeutics (United States)

National Institutes of Health

National Institute of Neurological Disorders and Stroke

Johns Hopkins Medicine

Lesley A. Kane is an author at Johns Hopkins University specializing in life sciences, molecular biology, and biochemistry.

ORCID

Publications per year

2006–2024

23

Publications

23

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Michael Lazarou, Danielle A. Sliter, Lesley A. Kane et al. · Nature · 2015 · 2.7K citations

, , +13

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

Seok Min Jin, Michael Lazarou, Chunxin Wang et al. · The Journal of Cell Biology · 2010 · 1.3K citations · Full text

, , +17

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

Lesley A. Kane, Michael Lazarou, Adam I. Fogel et al. · The Journal of Cell Biology · 2014 · 1.3K citations · Full text

, , +17

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

Derek P. Narendra, Lesley A. Kane, David N. Hauser et al. · Autophagy · 2010 · 783 citations · Full text

, , +17

Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin

Michael Lazarou, Seok Min Jin, Lesley A. Kane et al. · Developmental Cell · 2012 · 666 citations · Full text

, , +4

1–5 of 23