Lesley A. Kane

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Michael Lazarou, Danielle A. Sliter, Lesley A. Kane et al. · Nature · 2015 · 2.6K citations

Cell Autophagy, Mitophagy, Ubiquitin Kinase Pink1 +9

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

Seok Min Jin, Michael Lazarou, Chunxin Wang et al. · The Journal of Cell Biology · 2010 · 1.3K citations · Full text

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

Lesley A. Kane, Michael Lazarou, Adam I. Fogel et al. · The Journal of Cell Biology · 2014 · 1.3K citations · Full text

Cell Autophagy, Mitophagy, Selective Autophagy +14

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

Derek P. Narendra, Lesley A. Kane, David N. Hauser et al. · Autophagy · 2010 · 776 citations · Full text

Mitophagy, Parkin-induced Mitochondrial Clustering, Mitochondrial Dysfunction +22

Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin

Michael Lazarou, Seok Min Jin, Lesley A. Kane et al. · Developmental Cell · 2012 · 653 citations · Full text

Tom Complex, Signal Transduction, Organelle Dynamic +13