Concepedia

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Michael Lazarou, Danielle A. Sliter, Lesley A. Kane, Shireen A. Sarraf, Chunxin Wang, Jonathon L. Burman, Dionisia P. Sideris, Adam I. Fogel, Richard J. Youle

Nature · 2015 · 2.7K citations · 37 references

DOI

Concepts

References

37

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 7K citations · Full text

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra, Atsushi Tanaka, Der‐Fen Suen et al. · The Journal of Cell Biology · 2008 · 4K citations · Full text

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PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Sven Geisler, Kira M. Holmström, Diana Skujat et al. · Nature Cell Biology · 2010 · 2.8K citations

, , +12