Sven Geisler

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Sven Geisler, Kira M. Holmström, Diana Skujat et al. · Nature Cell Biology · 2010 · 2.7K citations

Cell Autophagy, Mitophagy, Autophagy +5

The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations

Sven Geisler, Kira M. Holmström, Angela Treis et al. · Autophagy · 2010 · 303 citations

Cell Autophagy, Mitophagy, Neurodegenerative Diseases +14

Hyperglycemia Impairs Proteasome Function by Methylglyoxal

Markus A. Queisser, Dachun Yao, Sven Geisler et al. · Diabetes · 2009 · 194 citations · Full text

VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease

Emiko Miura, Takafumi Hasegawa, Masatoshi Konno et al. · Neurobiology of Disease · 2014 · 194 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Synaptic Signaling +7

Harnessing human ADAR2 for RNA repair – Recoding a PINK1 mutation rescues mitophagy

Jacqueline Wettengel, Philipp Reautschnig, Sven Geisler et al. · Nucleic Acids Research · 2016 · 123 citations · Full text

Mitophagy, Engineering, Genetics +17