Concepedia

Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells

Jun Yamamoto, Qinghong Han, Sachiko Inubushi, Norihiko Sugisawa, Kazuyuki Hamada, Hiroto Nishino, Kentaro Miyake, Takafumi Kumamoto, Ryusei Matsuyama, Michael Bouvet,

Biochemical and Biophysical Research Communications · 2020 · 88 citations · 22 references

DOI

Concepts

References

22

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

Samantha J. Mentch, Mahya Mehrmohamadi, Lei Huang et al. · Cell Metabolism · 2015 · 683 citations · Full text

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Methionine is a metabolic dependency of tumor-initiating cells

Zhenxun Wang, Lian Yee Yip, Jia Hui Jane Lee et al. · Nature Medicine · 2019 · 393 citations

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High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.

Robert M. Hoffman, Richard W. Erbe · Proceedings of the National Academy of Sciences · 1976 · 298 citations

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The Effect of Replacement of Methionine by Homocystine on Survival of Malignant and Normal Adult Mammalian Cells in Culture

B. Halpern, Brian R. Clark, Dorothy Hardy et al. · Proceedings of the National Academy of Sciences · 1974 · 204 citations · Full text

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