Norihiko Sugisawa

Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells

Jun Yamamoto, Qinghong Han, Sachiko Inubushi et al. · Biochemical and Biophysical Research Communications · 2020 · 83 citations

Histone Modifications, Chromatin, Chromatin Remodeling +11

Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model

Takashi Higuchi, Kei Kawaguchi, Kentaro Miyake et al. · Anticancer Research · 2018 · 73 citations · Full text

Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

Jun Yamamoto, Sachiko Inubushi, Qinghong Han et al. · iScience · 2022 · 56 citations · Full text

Oncology, Excess Transmethylation Reactions, Methionine Addiction +11

Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma

Takashi Higuchi, Hiromichi Oshiro, Kentaro Miyake et al. · Anticancer Research · 2019 · 50 citations · Full text

Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model

Hiromichi Oshiro, Yasunori Tome, Tasuku Kiyuna et al. · Anticancer Research · 2019 · 44 citations · Full text