Qinghong Han

Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity

Shuya Yano, Shukuan Li, Qinghong Han et al. · Oncotarget · 2014 · 115 citations · Full text

Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer

Kei Kawaguchi, Kentaro Miyake, Qinghong Han et al. · Cancer Letters · 2018 · 85 citations

Oral Recombinant Methioninase, Oncology, Pancreatic Cancer +6

Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells

Jun Yamamoto, Qinghong Han, Sachiko Inubushi et al. · Biochemical and Biophysical Research Communications · 2020 · 83 citations

Histone Modifications, Chromatin, Chromatin Remodeling +11

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model

Takashi Murakami, Shukuan Li, Qinghong Han et al. · Oncotarget · 2017 · 81 citations · Full text

Polyethylene Glycol Conjugation of Recombinant Methioninase for Cancer Therapy

Yuying Tan, Xinghua Sun, Mingxu Xu et al. · Protein Expression and Purification · 1998 · 77 citations

Polyethylene Glycol Conjugation, Polymer-drug Conjugate, Bioconjugation +2