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Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study

Vivo StudyMedicinal ChemistryPharmaceutical ScienceBiochemistryMedicineNatural SciencesRational Drug DesignStructure-activity RelationshipTriazolothiadiazine DerivativesPharmacotherapyDrug DevelopmentPharmacologyDrug DiscoveryPharmaceutical ResearchDrug Resistance