Differential cytotoxicity of Combretastatins A1 and A4 in two daunorubicin-resistant P388 cell lines

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

George R. Pettit, Sheo B. Singh, Ernest Hamel et al. · Cellular and Molecular Life Sciences · 1989 · 789 citations

Life Sciences, Biochemistry, Cell Biology +11

Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein.

Marilyn M. Cornwell, Ira Pastan, Michael M. Gottesman · Journal of Biological Chemistry · 1987 · 535 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Isolation, Structure, and Synthesis of Combretastatins A-1 and B-1, Potent New Inhibitors of Microtubule Assembly, Derived from Combretum caffrum

George R. Pettit, Sheo B. Singh, Margaret L. Niven et al. · Journal of Natural Products · 1987 · 322 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structural and biochemical comparison of the anti-mitotic agents colchicine, combretastatin A4 and amphethinile.

AT McGown, BW Fox · PubMed · 1989 · 83 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Comparison of doxorubicin‐induced DNA damage in doxorubicin‐sensitive and ‐resistant P388 murine leukemia cells

Giovanni Capranico, Teresa Dasdia, Franco Zunino · International Journal of Cancer · 1986 · 43 citations

Medicine, Cancer Biology, Oncology +17