Giovanni Capranico

DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells

Alessio De Magis, Stefano Giustino Manzo, Marco Russo et al. · Proceedings of the National Academy of Sciences · 2018 · 333 citations

Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development

Giovanni Capranico, Stella Tinelli, Caroline A. Austin et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 1992 · 261 citations

Murine Development, Lineage Plasticity, Cell Lineage +7

Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin.

Christine Jaxel, Giovanni Capranico, Donna Kerrigan et al. · Journal of Biological Chemistry · 1991 · 199 citations · Full text

Chromatin, Cleavage Site, Biochemistry +11

In hepatocellular carcinoma <i>miR‐519d</i> is up‐regulated by p53 and DNA hypomethylation and targets <i>CDKN1A/p21, PTEN, AKT3</i> and <i>TIMP2</i>

Francesca Fornari, Maddalena Milazzo, Pasquale Chieco et al. · The Journal of Pathology · 2012 · 192 citations · Full text

Mir-519d Belongs, Pathology, Cell Death +20

Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin

Giovanni Capranico, Kurt W. Kohn, Yves Pommier · Nucleic Acids Research · 1990 · 186 citations · Full text