Caroline A. Austin

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia

Elaine Willmore, Sarah de Caux, Nicola J. Sunter et al. · Blood · 2004 · 266 citations · Full text

Medicine, Oncology, Pharmacology +13

Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development

Giovanni Capranico, Stella Tinelli, Caroline A. Austin et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 1992 · 263 citations

Life Sciences, Developmental Biology, Molecular Biology +6

The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage

Timothy J. Wendorff, Bryan H. Thurtle-Schmidt, Pauline Heslop et al. · Journal of Molecular Biology · 2012 · 234 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

γH2AX Foci Form Preferentially in Euchromatin after Ionising-Radiation

Ian G. Cowell, Nicola J. Sunter, Prim B. Singh et al. · PLoS ONE · 2007 · 219 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Digitoxin Inhibits the Growth of Cancer Cell Lines at Concentrations Commonly Found in Cardiac Patients

Miguel López‐Lázaro, Nuria Pastor, Marı́a Jesús Ayuso et al. · Journal of Natural Products · 2005 · 183 citations

Medicine, Oncology, Pharmacology +15