Marilyn M. Cornwell

Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein.

Marilyn M. Cornwell, Ira Pastan, Michael M. Gottesman · Journal of Biological Chemistry · 1987 · 535 citations · Full text

Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins.

Donglai Shen, Carol Cardarelli, Jinyoung Hwang et al. · Journal of Biological Chemistry · 1986 · 466 citations · Full text

Pathology, Cancer Biology, Tumor Biology +17

The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

Kazumitsu Ueda, Marilyn M. Cornwell, Michael M. Gottesman et al. · Biochemical and Biophysical Research Communications · 1986 · 413 citations

Glycosylation, Molecular Biology, Mdrl Gene +1

Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling.

Marilyn M. Cornwell, Ahmad R. Safa, Ronald L. Felsted et al. · Proceedings of the National Academy of Sciences · 1986 · 340 citations · Full text

Proteinlipid Interaction, Protein Secretion, Molecular Biology +22

Single cell analysis of daunomycin uptake and efflux in multidrug-resistant and -sensitive KB cells: effects of verapamil and other drugs.

Mark C. Willingham, Marilyn M. Cornwell, Carol Cardarelli et al. · PubMed · 1986 · 310 citations

Nuclear Fluorescence, Cell Culture, Inherent Fluorescence +21