Carol Cardarelli

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Kazumitsu Ueda, Carol Cardarelli, Michael M. Gottesman et al. · Proceedings of the National Academy of Sciences · 1987 · 1.1K citations · Full text

Full-length Cdna, Immunology, Molecular Biology +16

HIV-1 Protease Inhibitors Are Substrates for the<i>MDR</i>1 Multidrug Transporter

Caroline Lee, Michael M. Gottesman, Carol Cardarelli et al. · Biochemistry · 1998 · 481 citations

Protease Inhibitors, Biochemistry, Medicine +14

Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins.

Donglai Shen, Carol Cardarelli, Jinyoung Hwang et al. · Journal of Biological Chemistry · 1986 · 466 citations · Full text

Pathology, Cancer Biology, Tumor Biology +17

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis.

Suresh V. Ambudkar, Isabelle H. Lelong, J Zhang et al. · Proceedings of the National Academy of Sciences · 1992 · 397 citations · Full text

Drug-stimulatable Atp Hydrolysis, Molecular Pharmacology, Atpase Activity +15

α-Galactosidase A deficient mice: A model of Fabry disease

Toshio Ohshima, Gary J. Murray, William D. Swaim et al. · Proceedings of the National Academy of Sciences · 1997 · 362 citations · Full text