Xian‐Sen Huo

Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines

Xian‐Sen Huo, Xie‐Er Jian, Jie Ouyang et al. · European Journal of Medicinal Chemistry · 2021 · 52 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9

Synthesis, and biological evaluation of 3,6-diaryl-[1,2,4]triazolo[4,3-a]pyridine analogues as new potent tubulin polymerization inhibitors

Fang Yang, Xie‐Er Jian, Peng-Cheng Diao et al. · European Journal of Medicinal Chemistry · 2020 · 45 citations

Medicinal Chemistry, Biochemistry, Medicine +7

Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study

Weifeng Ma, Peng Chen, Xian‐Sen Huo et al. · European Journal of Medicinal Chemistry · 2020 · 44 citations

Vivo Study, Medicinal Chemistry, Pharmaceutical Science +12

Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors

Qiu Li, Xie‐Er Jian, Zhi-Ru Chen et al. · Bioorganic Chemistry · 2020 · 33 citations

Bioorganic Chemistry, Medicine, Benzofuran-based 3,4,5-Trimethoxybenzamide Derivatives +6

Rational design, synthesis and biological evaluation of novel 2-(substituted amino)-[1,2,4]triazolo[1,5-a]pyrimidines as novel tubulin polymerization inhibitors

Lin Chen, Tangyang Ji, Xian‐Sen Huo et al. · European Journal of Medicinal Chemistry · 2022 · 24 citations

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +11