Mathew P. Leese

Class III β-tubulin expression and in vitro resistance to microtubule targeting agents

Chloé Stengel, Stephen T. Newman, Mathew P. Leese et al. · British Journal of Cancer · 2009 · 191 citations · Full text

Medicine, Oncology, Pharmacology +16

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure

Wolfgang Döhle, Fabrice Jourdan, Grégory Menchon et al. · Journal of Medicinal Chemistry · 2017 · 130 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents

Christopher R. Ireson, Surinder K. Chander, A. Purohit et al. · British Journal of Cancer · 2004 · 120 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12

2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents:  Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity

Mathew P. Leese, Bertrand Leblond, Andrew Smith et al. · Journal of Medicinal Chemistry · 2006 · 108 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

A-Ring-Substituted Estrogen-3-<i>O</i>-sulfamates:  Potent Multitargeted Anticancer Agents

Mathew P. Leese, Hatem A Hejaz, Mary F. Mahon et al. · Journal of Medicinal Chemistry · 2005 · 75 citations · Full text

Medicine, Oncology, Pharmacology +14