Christopher R. Ireson

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

Ricky A. Sharma, Heather R. McLelland, K A Hill et al. · PubMed · 2001 · 829 citations

Medicine, Oncology, Pharmacology +13

Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.

Christopher R. Ireson, S Orr, Donald J. L. Jones et al. · PubMed · 2001 · 592 citations

Medicine, Biochemistry, Pharmacology +13

Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.

Christopher R. Ireson, Donald J. L. Jones, Samantha Orr et al. · PubMed · 2002 · 562 citations

Medicine, Biochemistry, Pharmacology +12

Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels.

Ricky A. Sharma, Christopher R. Ireson, Richard D. Verschoyle et al. · PubMed · 2001 · 213 citations

Life Sciences, Biochemistry, Pharmacology +16

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

Aimable Nahimana, Antoine Attinger, Dominique Aubry et al. · Blood · 2009 · 186 citations · Full text

Medicine, Oncology, Pharmacology +11