Potent anti-myeloma efficacy of dendritic cell therapy in combination with pomalidomide and programmed death-ligand 1 blockade in a preclinical model of multiple myeloma

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

Life Sciences, Immunology, Pathology +17

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

Haidong Dong, Scott E. Strome, Diva R. Salomão et al. · Nature Medicine · 2002 · 5K citations

Life Sciences, Immunology, Oncology +17

Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma

Caroline Robert, L. Thomas, Igor Bondarenko et al. · New England Journal of Medicine · 2011 · 4.5K citations · Full text

Medicine, Oncology, Pharmacotherapy +12

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Loise M. Francisco, Victor H. Salinas, Keturah Brown et al. · The Journal of Experimental Medicine · 2009 · 2K citations · Full text

Life Sciences, Cell Biology, Immunology +16

Tissue expression of PD-L1 mediates peripheral T cell tolerance

Mary Keir, Spencer C. Liang, Indira Guleria et al. · The Journal of Experimental Medicine · 2006 · 1.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17