Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

Life Sciences, Immunology, Pathology +17

Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

Yasumasa Ishida, Yasutoshi Agata, Kei‐ichi Shibahara et al. · The EMBO Journal · 1992 · 3.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

Hiroyuki Nishimura, Masato Nose, Hiroshi Hiai et al. · Immunity · 1999 · 2.7K citations · Full text

Life Sciences, Genetics, Immunology +15

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

Haidong Dong, Gefeng Zhu, Koji Tamada et al. · Nature Medicine · 1999 · 2.5K citations

Life Sciences, Cell Biology, Immunology +10

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

Thomas S. Griffith, Thomas Brunner, Sharon M. Fletcher et al. · Science · 1995 · 2K citations

Medicine, Immunology, Ophthalmology +17