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Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

Hiroyuki Nishimura, Masato Nose, Hiroshi Hiai, Nagahiro Minato, Tasuku Honjo

Immunity · 1999 · 2.7K citations · 44 references

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References

44

Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

Yasumasa Ishida, Yasutoshi Agata, Kei‐ichi Shibahara et al. · The EMBO Journal · 1992 · 3.2K citations · Full text

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T cell tolerance by clonal elimination in the thymus

John W. Kappler, Neal W. Roehm, Philippa Marrack · Cell · 1987 · 2.2K citations

, , +14

Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

Yasutoshi Agata, Hiroyuki Nishimura, Yasumasa Ishida et al. · International Immunology · 1996 · 1.6K citations

, , +10

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease.

Andreas Strasser, Senga Whittingham, David L. Vaux et al. · Proceedings of the National Academy of Sciences · 1991 · 868 citations

, , +17

Augmented humoral and anaphylactic responses in FcγRII-deficient mice

Toshiyuki Takai, Masao Ono, Masaki Hikida et al. · Nature · 1996 · 828 citations

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