Tasuku Honjo

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

Life Sciences, Immunology, Pathology +17

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan et al. · Cell · 2000 · 3.4K citations

Life Sciences, Genetics, Molecular Biology +14

Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

Yasumasa Ishida, Yasutoshi Agata, Kei‐ichi Shibahara et al. · The EMBO Journal · 1992 · 3.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

Yoshiko Iwai, Masayoshi Ishida, Yoshimasa Tanaka et al. · Proceedings of the National Academy of Sciences · 2002 · 3.2K citations

Life Sciences, Immunology, Oncology +17

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

Life Sciences, Cell Biology, Immunology +14