Concepedia

HIF-1α induces hypoxic apoptosis of MLO-Y4 osteocytes via JNK/caspase-3 pathway and the apoptotic-osteocyte-mediated osteoclastogenesis in vitro

Xiwen Song, Yi Tang, Jie Zhu, Yuanye Tian, Zhao-Hui Song, Xiu Feng Hu, Yun Cai, Feiwu Kang

Tissue and Cell · 2020 · 34 citations · 38 references

DOI

Concepts

References

38

HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

, , +17

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana et al. · Cell Metabolism · 2006 · 2.2K citations · Full text

, , +12

Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

Cathy Tournier, Patricia Hess, Derek Yang et al. · Science · 2000 · 1.7K citations

, , +17

Direct measurement of local oxygen concentration in the bone marrow of live animals

Joel A. Spencer, Francesca Ferraro, Emmanuel Roussakis et al. · Nature · 2014 · 1.1K citations · Full text

, , +16

Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis

Suparna Mazumder, Dragos Plesca, Alexandru Almasan · Humana Press eBooks · 2008 · 362 citations

, , +11