Efficient Gene Targeting in Maize Using Inducible CRISPR-Cas9 and Marker-free Donor Template

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

Life Sciences, Genetics, Molecular Genetics +16

Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

Giedrius Gasiūnas, Rodolphe Barrangou, Philippe Horvath et al. · Proceedings of the National Academy of Sciences · 2012 · 2.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Y G Kim, Srinivasan Chandrasegaran · Proceedings of the National Academy of Sciences · 1996 · 2.1K citations

Life Sciences, Biotechnology, Molecular Biology +15

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew

Yanpeng Wang, Xi Cheng, Yi Zhang et al. · Nature Biotechnology · 2014 · 2K citations

Agriculture, Genetics, Plant Sciences +12