Concepedia

Feedback activation of EGFR is the main cause for STAT3 inhibition-irresponsiveness in pancreatic cancer cells

Chengguang Zhao, Lehe Yang, Feng Zhou, Yun Yu, Xiaojing Du, Youqun Xiang, Chenglong Li, Xiaoying Huang, Congying Xie, Zhiguo Liu,

Oncogene · 2020 · 37 citations · 32 references

DOI

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References

32

Cancer statistics, 2019

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2019 · 21K citations · Full text

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A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

Longchuan Bai, Haibin Zhou, Renqi Xu et al. · Cancer Cell · 2019 · 618 citations · Full text

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Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

Hanane Laklai, Yekaterina A. Miroshnikova, Michael W. Pickup et al. · Nature Medicine · 2016 · 601 citations · Full text

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis <i>in vivo</i>

Jennifer R. Grandis, Stephanie D. Drenning, Qing Zeng et al. · Proceedings of the National Academy of Sciences · 2000 · 593 citations

, , +10

Drug Resistance via Feedback Activation of Stat3 in Oncogene-Addicted Cancer Cells

Ho-June Lee, Guanglei Zhuang, Yi Cao et al. · Cancer Cell · 2014 · 562 citations · Full text

, , +16