Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp<sup>2</sup>)–C(sp<sup>3</sup>) Cross-Coupling Methods by Library Synthesis

Amanda W. Dombrowski, Nathan J. Gesmundo, Ana L. Aguirre, Katerina A. Sarris, Jonathon M. Young, Andrew R. Bogdan, M. Cynthia Martin, Shasline Gedeon, Ying Wang

ACS Medicinal Chemistry Letters · 2020 · 233 citations · 31 references

DOIFull text

Open access

Concepts

Abstract

) coupling methods, like tertiary group installation. The results reported herein should be used to inform future syntheses, assess reaction scope, and encourage medicinal chemists to expand their synthetic toolbox.

References

31