Concepedia

Alkyl Cross-coupling

Alkyl Cross-Coupling is a type of transition metal-catalyzed cross-coupling reaction in which an alkyl electrophile or nucleophile is coupled with a distinct coupling partner to form a new carbon–carbon bond, distinguished from aryl- or vinyl-based cross-coupling reactions by the involvement of sp³-hybridized alkyl frameworks that present unique challenges in reactivity and stereocontrol.

672

Publications

52.8K

Citations

2K

Authors

473

Institutions

Publications per year

2017–2026

219

Parents

Publications

672

Catalysts for Cross‐Coupling Reactions with Non‐activated Alkyl Halides

Anja C. Frisch, Matthias Beller · Angewandte Chemie International Edition · 2005 · 915 citations

, , +15

The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis

Sherry R. Chemler, Dirk Trauner, Samuel J. Danishefsky · Angewandte Chemie International Edition · 2001 · 908 citations

, , +8

Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II): an effective catalyst for cross-coupling of secondary and primary alkyl Grignard and alkylzinc reagents with organic halides

Tamio Hayashi, Mitsuo Konishi, Yuji Kobori et al. · Journal of the American Chemical Society · 1984 · 747 citations

, , +11

A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents

Tian Qin, Josep Cornellà, Chao Li et al. · Science · 2016 · 744 citations

, , +15

Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective

Xile Hu · Chemical Science · 2011 · 599 citations · Full text

, , +15

1–5 of 672

Authors

2K

  1. GC
    Gregory C. Fu

    Massachusetts Institute of Technology, United States

    30 publications · 4.9K citations

    28

    h-index

  2. NK
    Nobuaki Kambe

    The University of Osaka, Japan

    17 publications · 1.5K citations

    17

    h-index

  3. GA
    Gary A. Molander

    University of Pennsylvania, United States

    17 publications · 2.3K citations

    17

    h-index

  4. XH
    Xile Hu

    École Polytechnique Fédérale de Lausanne, Switzerland

    12 publications · 1.6K citations

    12

    h-index

  5. JT
    Jun Terao

    Kyoto University, Japan

    12 publications · 1.2K citations

    12

    h-index

1–5 of 2K

Institutions

473

  1. Massachusetts Institute of Technology

    Cambridge, United States

    25 h-index

    67 publications

    11K citations

  2. Kyoto University

    Kyoto, Japan

    24 h-index

    103 publications

    6.6K citations

  3. University of Science and Technology of China

    Hefei, China

    20 h-index

    103 publications

    8.6K citations

  4. The University of Osaka

    Osaka, Japan

    20 h-index

    91 publications

    7.9K citations

  5. University of Pennsylvania

    Philadelphia, United States

    19 h-index

    61 publications

    9K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    65 publications

    4K citations

  7. Chinese Academy of Sciences

    Beijing, China

    16 h-index

    56 publications

    4.3K citations

  8. Shanghai Institute of Organic Chemistry

    Shanghai, China

    14 h-index

    44 publications

    3.3K citations

1–8 of 473

Venues

  1. Journal of the American Chemical Society

    JACS · 86 publications · 14K citations

    65

    h-index

  2. Angewandte Chemie International Edition

    70 publications · 9.7K citations

    53

    h-index

  3. Organic Letters

    OL · 97 publications · 5.8K citations

    46

    h-index

  4. The Journal of Organic Chemistry

    JOC · 57 publications · 3K citations

    34

    h-index

  5. Chemical Communications

    ChemComm · 32 publications · 2K citations

    27

    h-index

1–5