Concepedia

Combinatorial Library Synthesis

Combinatorial Library Synthesis is a chemical methodology in drug discovery and materials science that systematically generates a diverse collection of molecules by combining sets of building blocks in all possible permutations, thereby enabling high-throughput screening for desired properties.

1K

Publications

61.6K

Citations

3.9K

Authors

873

Institutions

Publications per year

2017–2026

116

Parents

Publications

1K

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

Richard A. Houghten, Clemencia Pinilla, Sylvie E. Blondelle et al. · Nature · 1991 · 1.3K citations

, , +16

Multiple-Component Condensation Strategies for Combinatorial Library Synthesis

Robert W. Armstrong, Andrew P. Combs, Paul Tempest et al. · Accounts of Chemical Research · 1996 · 1.1K citations

, , +7

Maximizing Synthetic Efficiency: Multi-Component Transformations Lead the Way

Hugues Bienaymé, Chris Hulme, G. ODDON et al. · Chemistry - A European Journal · 2000 · 1.1K citations · Full text

, , +17

A Combinatorial Approach to Materials Discovery

X.‐D. Xiang, Xiaodong Sun, G. Briceño et al. · Science · 1995 · 1K citations

, , +17

Encoded combinatorial chemistry.

Sydney Brenner, Richard A. Lerner · Proceedings of the National Academy of Sciences · 1992 · 1K citations

, , +17

1–5 of 1K

Authors

3.9K

  1. JK
    Jeremy K. M. Sanders

    University of Cambridge, United Kingdom

    22 publications · 1.8K citations

    22

    h-index

  2. RA
    Richard A. Houghten

    Torrey Pines Institute For Molecular Studies, United States

    16 publications · 2.1K citations

    14

    h-index

  3. TT
    Takashi Takahashi

    Tokyo Institute of Technology, Japan

    11 publications · 404 citations

    11

    h-index

  4. EM
    Eric M. Gordon

    Bristol-Myers Squibb (United States), United States

    10 publications · 1.1K citations

    10

    h-index

  5. AG
    A. Ganesan

    University of Southampton, United Kingdom

    10 publications · 471 citations

    10

    h-index

1–5 of 3.9K

Institutions

873

  1. Scripps Research Institute

    San Diego, United States

    27 h-index

    152 publications

    15.5K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    27 h-index

    113 publications

    8.2K citations

  3. Torrey Pines Institute For Molecular Studies

    San Diego, United States

    19 h-index

    80 publications

    13.4K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    76 publications

    4.3K citations

  5. Affymax (United States)

    Cupertino, United States

    13 h-index

    60 publications

    4.2K citations

  6. University of California San Diego

    San Diego, United States

    13 h-index

    45 publications

    5.8K citations

  7. University of California, Berkeley

    Berkeley, United States

    12 h-index

    33 publications

    7.6K citations

  8. Tokyo Institute of Technology

    Tokyo, Japan

    12 h-index

    57 publications

    2.1K citations

1–8 of 873

Venues

  1. Journal of the American Chemical Society

    JACS · 45 publications · 5.4K citations

    40

    h-index

  2. Journal of Combinatorial Chemistry

    79 publications · 3K citations

    32

    h-index

  3. Angewandte Chemie International Edition

    36 publications · 3.4K citations

    30

    h-index

  4. Tetrahedron Letters

    52 publications · 2.2K citations

    28

    h-index

  5. The Journal of Organic Chemistry

    JOC · 35 publications · 2.5K citations

    28

    h-index

1–5