Concepedia

Library Design

Library Design is the systematic planning and construction of a focused or diverse collection of chemical or biological entities, distinguished by its strategic selection of building blocks and structural features to optimize the exploration of molecular space for drug discovery or functional optimization within combinatorial chemistry, computational medicinal chemistry, directed evolution, and synthetic medicinal chemistry.

1.7K

Publications

93.4K

Citations

4.7K

Authors

1.2K

Institutions

Publications per year

2017–2026

271

Parents

Children

Publications

1.7K

A simple and very efficient method for generating cDNA libraries

Ueli Gubler, Beth J. Hoffman · Gene · 1983 · 4.6K citations

, , +10

A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases

Arup K. Ghose, Vellarkad N. Viswanadhan, John J. Wendoloski · Journal of Combinatorial Chemistry · 1998 · 3K citations

, , +14

New Basis Set Exchange: An Open, Up-to-Date Resource for the Molecular Sciences Community

Benjamin P. Pritchard, Doaa Altarawy, Brett Didier et al. · Journal of Chemical Information and Modeling · 2019 · 2.3K citations

, , +9

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

Dean G. Brown, Jonas Boström · Journal of Medicinal Chemistry · 2015 · 2K citations · Full text

, , +11

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

Richard A. Houghten, Clemencia Pinilla, Sylvie E. Blondelle et al. · Nature · 1991 · 1.3K citations

, , +16

1–5 of 1.7K

Authors

4.7K

  1. GS
    Gisbert Schneider

    ETH Zurich, Switzerland

    16 publications · 1.3K citations

    13

    h-index

  2. JK
    Jeremy K. M. Sanders

    University of Cambridge, United Kingdom

    13 publications · 1.5K citations

    13

    h-index

  3. RA
    Richard A. Houghten

    Torrey Pines Institute For Molecular Studies, United States

    12 publications · 2.2K citations

    12

    h-index

  4. JL
    José L. Medina‐Franco

    Universidad Nacional Autónoma de México, Mexico

    11 publications · 692 citations

    11

    h-index

  5. DN
    Dario Neri

    ETH Zurich, Switzerland

    11 publications · 1.1K citations

    11

    h-index

1–5 of 4.7K

Institutions

1.2K

  1. Scripps Research Institute

    San Diego, United States

    23 h-index

    98 publications

    11K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    21 h-index

    54 publications

    5.4K citations

  3. University of Sheffield

    Sheffield, United Kingdom

    18 h-index

    47 publications

    3.6K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    98 publications

    3.8K citations

  5. Torrey Pines Institute For Molecular Studies

    San Diego, United States

    17 h-index

    71 publications

    13.9K citations

  6. ETH Zurich

    Zurich, Switzerland

    16 h-index

    95 publications

    7.2K citations

  7. Roche (Switzerland)

    Basel, Switzerland

    14 h-index

    40 publications

    13K citations

  8. Harvard University

    Cambridge, United States

    14 h-index

    53 publications

    4.9K citations

1–8 of 1.2K

Venues

  1. 36

    h-index

  2. Journal of Medicinal Chemistry

    40 publications · 5.5K citations

    31

    h-index

  3. Journal of Chemical Information and Modeling

    JCIM · 58 publications · 5.3K citations

    30

    h-index

  4. Journal of Combinatorial Chemistry

    44 publications · 4.9K citations

    27

    h-index

  5. The Journal of Academic Librarianship

    61 publications · 2.3K citations

    27

    h-index

1–5