Concepedia

Publication | Open Access

AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia

DOIFull Paper Access

62

Citations

45

References

2020

Year

Yi Xue, Aloke Sarkar, Burcu Aslan, Mary Ayres, LaKesla R. Iles, Michael J. Keating, William G. Wierda, James P. Long, Maria Teresa Sabrina Bertilaccio, Varsha Gandhi
Clinical Cancer Research

Abstract

AMG-176 is active in inducing CLL cell death while sparing normal blood cells. Combination with low-dose venetoclax was additive or synergistic.

References

YearCitations

Page 1