Concepedia

Bcl-2 Protein Expression

Bcl-2 Protein Expression is a molecular biomarker phenomenon referring to the measurable synthesis and accumulation of Bcl-2 family proteins in cells, distinguished by its role in regulating mitochondrial apoptosis through differential expression levels that influence cellular survival and death decisions.

7.4K

Publications

485.5K

Citations

37.2K

Authors

4.7K

Institutions

Publications per year

2017–2026

1.2K

Parents

Publications

7.4K

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

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<i>miR-15</i> and <i>miR-16</i> induce apoptosis by targeting BCL2

Amelia Cimmino, George A. Calin, Muller Fabbri et al. · Proceedings of the National Academy of Sciences · 2005 · 3.5K citations · Full text

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Bcl-2 functions in an antioxidant pathway to prevent apoptosis

David M. Hockenbery, Zoltán N. Oltvai, Xiao-Ming Yin et al. · Cell · 1993 · 3.4K citations

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

David L. Vaux, Suzanne Cory, Jerry M. Adams · Nature · 1988 · 3.2K citations

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Lawrence Boise, Maribel González‐García, C E Postema et al. · Cell · 1993 · 3.1K citations · Full text

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1–5 of 7.4K

Authors

37.2K

  1. JC
    John C. Reed

    Sanford Burnham Prebys Medical Discovery Institute, United States

    112 publications · 16.8K citations

    68

    h-index

  2. SK
    Stanisław Krajewski

    Sanford Burnham Prebys Medical Discovery Institute, United States

    47 publications · 9K citations

    38

    h-index

  3. TJ
    Timothy J. McDonnell

    The University of Texas MD Anderson Cancer Center, United States

    39 publications · 4.3K citations

    30

    h-index

  4. GN
    Gabriel Núñez

    University of Michigan, United States

    31 publications · 12.4K citations

    29

    h-index

  5. AS
    Andreas Strasser

    Walter and Eliza Hall Institute of Medical Research, Australia

    36 publications · 8.7K citations

    28

    h-index

1–5 of 37.2K

Institutions

4.7K

  1. Sanford Burnham Prebys Medical Discovery Institute

    La Jolla, United States

    65 h-index

    307 publications

    64.8K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    60 h-index

    723 publications

    65.6K citations

  3. Stanford University

    Stanford, United States

    51 h-index

    252 publications

    32.7K citations

  4. Inserm

    Paris, France

    50 h-index

    548 publications

    47.8K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    50 h-index

    164 publications

    101.4K citations

  6. University of Michigan

    Ann Arbor, United States

    47 h-index

    278 publications

    43.2K citations

  7. Harvard University

    Cambridge, United States

    44 h-index

    273 publications

    33K citations

  8. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    43 h-index

    322 publications

    68.6K citations

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Venues

  1. PubMed

    Repository · 792 publications · 53.9K citations

    110

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  2. Blood

    156 publications · 22.5K citations

    79

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  3. Journal of Biological Chemistry

    JBC · 131 publications · 17.3K citations

    70

    h-index

  4. The Journal of Immunology

    JI · 104 publications · 10.3K citations

    60

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 63 publications · 17.4K citations

    55

    h-index

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