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Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models

Rachel Kuta, Nancy Larochelle, Mario I. Fernández, Arun Pal, Sandra Minotti, Michael Tibshirani, Kyle St. Louis, Benoît J. Gentil, Joséphine Nalbantoglu, Andreas Hermann,

Cell Stress and Chaperones · 2020 · 54 citations · 59 references

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References

59

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

D.R. Rosen, Teepu Siddique, David T. Patterson et al. · Nature · 1993 · 7K citations

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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Caroline Vance, Boris Rogelj, Tibor Hortobágyi et al. · Science · 2009 · 2.5K citations · Full text

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Mutations in the <i>FUS/TLS</i> Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

Thomas J. Kwiatkowski, Daryl A. Bosco, Aurélie Leclerc et al. · Science · 2009 · 2.5K citations

, , +14

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

Purva Bali, Michael Pranpat, James E. Bradner et al. · Journal of Biological Chemistry · 2005 · 746 citations · Full text

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

Sandy D. Westerheide, Julius Anckar, Stanley M. Stevens et al. · Science · 2009 · 709 citations

, , +19