Concepedia

James E. Bradner

JE

Statistics

Publications

46

Citations

11.1K

H-Index

38

Active since

1999

Affiliations

Dana-Farber Cancer Institute(Current)

Harvard University

Brigham and Women's Hospital

Broad Institute

Massachusetts General Hospital

James E. Bradner is an author at Dana-Farber Cancer Institute specializing in molecular oncology, oncology, and molecular biology.

Publications per year

1999–2022

46

Publications

46

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

Purva Bali, Michael Pranpat, James E. Bradner et al. · Journal of Biological Chemistry · 2005 · 749 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma

Loredana Santo, Teru Hideshima, Andrew L. Kung et al. · Blood · 2012 · 601 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression

Hengrui Zhu, Fee Bengsch, Nikolaos Svoronos et al. · Cell Reports · 2016 · 431 citations · Full text

Medicine, Immunology, Oncology +17

BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure

Priti Anand, Jonathan D. Brown, Charles Y. Lin et al. · Cell · 2013 · 410 citations · Full text

Life Sciences, Cardiology, Molecular Biology +10

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