Jonathan D. Brown

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

Shaokun Shu, Charles Y. Lin, Housheng Hansen He et al. · Nature · 2016 · 616 citations · Full text

Breast Oncology, Medicine, Immunology +9

NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

Jonathan D. Brown, Charles Y. Lin, Qiong Duan et al. · Molecular Cell · 2014 · 614 citations · Full text

Inflammation, Inflammatory Disease, Immunology +7

In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice

Luke W. Koblan, Michael R. Erdos, Christopher Wilson et al. · Nature · 2021 · 467 citations · Full text

Knockout Mouse, Developmental Biology, Degenerative Disease +3

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression

Rajat M. Gupta, Joseph Hadaya, Aditi Trehan et al. · Cell · 2017 · 450 citations · Full text

Genetic Variant Associated, Vascular Disease, Vascular Adaptation +10

BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure

Priti Anand, Jonathan D. Brown, Charles Y. Lin et al. · Cell · 2013 · 404 citations · Full text

Transcriptional Regulation, Heart Failure, Cardiomyopathy +6