A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Suhas S.P. Rao, Miriam Huntley, Neva C. Durand, +8

Cell

ChromatinFunctional GenomicsChromatin StructureChromatin RemodelingNatural Sciences +12

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Erez Lieberman-Aiden, Nynke L. van Berkum, Louise Williams, +16

Science

Structural BioinformaticsGeneticsGenomic MechanismMolecular BiologyGenomics +19

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber, +1

Cell

Histone ModificationsChromatinDna Methyltransferases Dnmt3aDevelopmental BiologyEpigenetic Change +11

The ground state of embryonic stem cell self-renewal

Qi‐Long Ying, Jason Wray, Jennifer Nichols, +5

Nature

Embryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyMedicineAdult Stem Cell +7

Cooler: scalable storage for Hi-C data and other genomically labeled arrays

Nezar Abdennur, Leonid A. Mirny

Bioinformatics

Dense FormAbstract MotivationEngineeringGeneticsComputer Architecture +25

Multiscale 3D Genome Rewiring during Mouse Neural Development

Boyan Bonev, Netta Mendelson Cohen, Quentin Szabo, +8

Cell

Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

Alistair N. Boettiger, Bogdan Bintu, Jeffrey R. Moffitt, +7

Nature

ChromatinChromatin StructureChromatin RemodelingNatural SciencesEpigenetic Change +7

The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

Hendrik Marks, Tüzer Kalkan, Roberta Menafra, +8

Cell

Chromatin Compaction by a Polycomb Group Protein Complex

Nicole J. Francis, Robert E. Kingston, Christopher L. Woodcock

Science

GeneticsMolecular BiologyMolecular GeneticsEpigeneticsTranscriptional Regulation +16

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Ilya M. Flyamer, Johanna Gassler, Maxim Imakaev, +6

Nature