DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Suhas S.P. Rao, Miriam Huntley, Neva C. Durand et al. · Cell · 2014 · 9.4K citations · Full text

Chromatin, Functional Genomics, Chromatin Structure +14

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Erez Lieberman-Aiden, Nynke L. van Berkum, Louise Williams et al. · Science · 2009 · 9.3K citations · Full text

Structural Bioinformatics, Genetics, Genomic Mechanism +21

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6K citations · Full text

Histone Modifications, Chromatin, Dna Methyltransferases Dnmt3a +13

The ground state of embryonic stem cell self-renewal

Qi‐Long Ying, Jason Wray, Jennifer Nichols et al. · Nature · 2008 · 3.5K citations · Full text

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +9

Cooler: scalable storage for Hi-C data and other genomically labeled arrays

Nezar Abdennur, Leonid A. Mirny · Bioinformatics · 2019 · 1.8K citations · Full text

Dense Form, Abstract Motivation, Engineering +27